Motif ID: FOX{C1,C2}.p2

Z-value: 1.012


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)



Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74491272 2.329 ALB
albumin
chr12_+_99391870 2.019 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_99391681 1.880 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr4_-_100359353 1.644 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr14_-_93988838 1.587 NM_001080451
SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr1_-_36721010 1.445 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr3_-_115826481 1.416 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr14_+_94117511 1.404 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr14_+_94117483 1.239 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr7_+_99263571 1.177 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr20_+_42417752 1.159 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr3_+_186529376 1.115 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr5_+_140690387 1.107 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr10_+_7785347 1.098 ITIH2
inter-alpha (globulin) inhibitor H2
chr11_-_2113297 1.065 IGF2
insulin-like growth factor 2 (somatomedin A)
chr21_-_42608531 1.057 TFF3
trefoil factor 3 (intestinal)
chr17_-_61655915 1.057 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_+_7785360 1.010 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_74500748 1.002 ALB
albumin
chr10_+_7785290 0.945 ITIH2
inter-alpha (globulin) inhibitor H2
chr7_-_50600536 0.924 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr10_+_7785331 0.910 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_17125885 0.892 NM_001079827
CLRN2
clarin 2
chr4_+_71054492 0.878 NM_214711
C4orf40
chromosome 4 open reading frame 40
chr5_+_140454382 0.863 NM_018936
PCDHB2
protocadherin beta 2
chr22_+_16423147 0.849 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr2_-_88208650 0.826 NM_001443
FABP1
fatty acid binding protein 1, liver
chr17_+_19917420 0.770 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr10_+_7785235 0.758 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr9_-_74735669 0.738 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_-_35266305 0.723 PRLR
prolactin receptor
chr12_-_23995220 0.718 SOX5
SRY (sex determining region Y)-box 5
chrX_+_70438352 0.714 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr7_+_134483305 0.686 NM_018295
TMEM140
transmembrane protein 140
chr7_+_73826244 0.671 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr4_-_84254912 0.670 PLAC8
placenta-specific 8
chr17_-_7023378 0.652 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr1_+_151867483 0.635 NM_006271
S100A1
S100 calcium binding protein A1
chr19_-_47723183 0.635 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr22_+_49272078 0.625 NM_017584
MIOX
myo-inositol oxygenase
chr2_-_188127294 0.613 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr17_-_7023283 0.594 ASGR1
asialoglycoprotein receptor 1
chr3_+_134978615 0.593 TF
transferrin
chr4_-_84254873 0.591 PLAC8
placenta-specific 8
chr11_+_111294868 0.580 C11orf52
chromosome 11 open reading frame 52
chr1_+_111573855 0.577 NM_001025199
CHI3L2
chitinase 3-like 2
chr4_-_84254932 0.571 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr19_-_6671585 0.567 NM_000064
C3
complement component 3
chr9_-_103237851 0.561 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr14_+_94117545 0.556 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr13_+_96592051 0.552 MBNL2
muscleblind-like 2 (Drosophila)
chr22_-_28992787 0.552 NM_020530
OSM
oncostatin M
chr2_+_158666627 0.550 NM_173355
UPP2
uridine phosphorylase 2
chr2_-_233349469 0.534 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr11_+_111294810 0.525 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr7_-_98643024 0.522 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr17_-_16816113 0.513 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr3_-_33675484 0.511 CLASP2
cytoplasmic linker associated protein 2
chr20_+_56904042 0.504 GNAS
GNAS complex locus
chr7_+_104468614 0.492 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr6_-_138862271 0.490 NM_001144060
NHSL1
NHS-like 1
chr2_+_73864823 0.466 NM_001080474
C2orf78
chromosome 2 open reading frame 78
chr17_-_77233966 0.462 NM_002602
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr10_-_91393610 0.450 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr2_+_73973600 0.437 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_-_159386007 0.437 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr22_-_39189369 0.427 MKL1
megakaryoblastic leukemia (translocation) 1
chr2_-_216008689 0.422 FN1
fibronectin 1
chr10_-_82039158 0.419 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chrX_-_130250880 0.417 IGSF1
immunoglobulin superfamily, member 1
chr20_-_5982617 0.416 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr6_-_29163027 0.411 NM_001005226
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr1_+_179269689 0.408 MR1
major histocompatibility complex, class I-related
chr2_+_73973640 0.406 ACTG2
actin, gamma 2, smooth muscle, enteric
chr10_+_60607232 0.398 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr21_-_42608774 0.398 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr9_+_139265533 0.381 NM_001004353
C9orf173
chromosome 9 open reading frame 173
chr1_+_179269761 0.375 MR1
major histocompatibility complex, class I-related
chr12_-_101396459 0.372 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr2_-_174537354 0.369 SP3
Sp3 transcription factor
chr1_+_179269766 0.367 MR1
major histocompatibility complex, class I-related
chr11_-_6418705 0.367 NM_000613
HPX
hemopexin
chr10_+_111755715 0.362 NM_019903
ADD3
adducin 3 (gamma)
chr20_-_32924219 0.359 NM_178026
GGT7
gamma-glutamyltransferase 7
chr20_+_56903595 0.358 GNAS
GNAS complex locus
chr7_-_50596238 0.355 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_-_155788775 0.353 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr5_-_156468571 0.344 HAVCR2
hepatitis A virus cellular receptor 2
chr1_-_110735158 0.339 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr20_-_1321744 0.338 NM_000801
NM_054014
FKBP1A

FK506 binding protein 1A, 12kDa

chr20_-_1321702 0.337 FKBP1A-SDCBP2
FKBP1A
FKBP1A-SDCBP2 read-through transcript
FK506 binding protein 1A, 12kDa
chr1_+_198263352 0.335 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr2_+_102345528 0.333 NM_003855
IL18R1
interleukin 18 receptor 1
chr3_-_52688768 0.330 NM_018165
NM_181042
PBRM1

polybromo 1

chr6_-_138862273 0.329


chr6_+_31016755 0.328 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr6_-_131333173 0.327 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_+_189547377 0.325 COL3A1
collagen, type III, alpha 1
chr17_+_7402315 0.321 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr2_+_189547358 0.318 COL3A1
collagen, type III, alpha 1
chr1_+_200246370 0.318 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_-_36347197 0.313 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr9_-_94338072 0.312 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr14_-_23623657 0.312 NM_006177
NRL
neural retina leucine zipper
chr1_-_166965034 0.306 NM_001937
DPT
dermatopontin
chr10_+_24538094 0.305 KIAA1217
KIAA1217
chr18_-_54447168 0.299 NM_052947
ALPK2
alpha-kinase 2
chr17_+_46176105 0.298 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr10_+_86174665 0.295 FAM190B
family with sequence similarity 190, member B
chr17_-_33179118 0.290 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr6_+_142510075 0.285 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr14_-_93924663 0.283 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr11_-_116199145 0.281 NM_000482
APOA4
apolipoprotein A-IV
chr16_-_21130368 0.281 NM_003460
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr12_-_47735373 0.275 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr6_+_142510108 0.274 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr6_+_142510094 0.270 NM_016485
VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr2_-_37269193 0.267 NM_001032377
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr5_-_59819642 0.262 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_215998181 0.261 FN1
fibronectin 1
chr11_-_3759886 0.261 NUP98
nucleoporin 98kDa
chr4_+_186587537 0.257 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr11_+_65027721 0.256


chrX_-_130251068 0.254 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr21_+_42697058 0.253 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr4_+_38740246 0.253 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr4_-_184480572 0.251 NM_001185149
CLDN24
claudin 24
chr12_+_25096472 0.250 NM_006152
LRMP
lymphoid-restricted membrane protein
chr15_+_38843535 0.250 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_+_169747788 0.246 PRRC2C
proline-rich coiled-coil 2C
chr2_+_189547323 0.245 NM_000090
COL3A1
collagen, type III, alpha 1
chr4_+_146820805 0.242 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr2_-_188127430 0.242 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr1_-_24112345 0.240 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr2_+_161701711 0.239 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr17_+_70984173 0.235 KIAA0195
KIAA0195
chr7_-_56128098 0.233 NM_006213
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr14_-_93924873 0.230 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr11_+_111288686 0.229 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr6_+_142510034 0.225 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr6_+_155579788 0.224 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr4_-_159313167 0.224 NM_016613
FAM198B
family with sequence similarity 198, member B
chr19_+_47509274 0.221 NM_173633
TMEM145
transmembrane protein 145
chr8_+_55691179 0.220 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr14_-_23846904 0.218 CIDEB
cell death-inducing DFFA-like effector b
chr11_-_67163600 0.215 NM_005995
TBX10
T-box 10
chr1_-_56750235 0.213 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_190635566 0.213 NM_005259
MSTN
myostatin
chr20_-_1321571 0.212 FKBP1A
FK506 binding protein 1A, 12kDa
chr16_+_22011362 0.205 NM_173615
VWA3A
von Willebrand factor A domain containing 3A
chr2_-_158008763 0.204 NM_004288
CYTIP
cytohesin 1 interacting protein
chr13_-_98757634 0.203 NM_004951
GPR183
G protein-coupled receptor 183
chr11_-_16454493 0.202 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr16_+_68238460 0.201 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr8_+_103633023 0.199 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr3_-_120761092 0.199 NM_005191
CD80
CD80 molecule
chr2_+_108271526 0.199 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr14_+_99601517 0.198 EVL
Enah/Vasp-like
chr2_+_121271336 0.197 NM_005270
GLI2
GLI family zinc finger 2
chr12_-_23995109 0.197 SOX5
SRY (sex determining region Y)-box 5
chr9_-_14900992 0.191 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr16_+_80626456 0.190 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_+_8216416 0.188 NM_001004328
ZNF705A
zinc finger protein 705A
chr19_+_40895669 0.187 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr3_+_99733432 0.185 NM_005290
GPR15
G protein-coupled receptor 15
chr1_-_68688219 0.183 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr17_+_23875085 0.183 NM_003593
FOXN1
forkhead box N1
chr12_+_32546243 0.177 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_+_99601498 0.176 NM_016337
EVL
Enah/Vasp-like
chr3_-_42892195 0.175 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr10_-_104168559 0.175 PSD
pleckstrin and Sec7 domain containing
chr11_-_10787157 0.175 NM_001042559
NM_001418
EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

chr11_-_9182356 0.173 DENND5A
DENN/MADD domain containing 5A
chr5_+_176806401 0.173 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr5_+_140160966 0.173 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr2_-_70374284 0.172 SNRPG
small nuclear ribonucleoprotein polypeptide G
chr2_-_70374349 0.172 NM_003096
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr2_-_174968595 0.172 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr14_+_23527866 0.172 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2
chr8_-_125785611 0.169 MTSS1
metastasis suppressor 1
chr18_-_53438854 0.166


chr1_+_242281199 0.165 ZNF238
zinc finger protein 238
chr6_+_64414389 0.164 NM_015153
PHF3
PHD finger protein 3
chr11_-_61823078 0.164 NM_206998
SCGB1D4
secretoglobin, family 1D, member 4
chr1_+_154095883 0.162 NM_152280
SYT11
synaptotagmin XI
chr2_-_32089557 0.161 MEMO1
mediator of cell motility 1
chr1_-_205012348 0.161 NM_000572
IL10
interleukin 10
chr6_-_52818851 0.159 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr2_+_172530120 0.158 HAT1
histone acetyltransferase 1
chr20_+_9146036 0.158 NM_182797
PLCB4
phospholipase C, beta 4
chr14_-_34414603 0.158 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chr5_+_43645018 0.156 NNT
nicotinamide nucleotide transhydrogenase
chr11_+_117680504 0.152 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr3_+_153499883 0.152 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr11_+_111288669 0.152 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr4_-_159312973 0.151 FAM198B
family with sequence similarity 198, member B
chr7_+_94123672 0.149 PEG10
paternally expressed 10
chr1_-_25164061 0.149 NM_001031680
RUNX3
runt-related transcription factor 3
chr10_-_112668892 0.148 NM_001195304
NM_001195305
NM_001195307
BBIP1


BBSome interacting protein 1


chr8_+_20099169 0.147 ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.